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Epigenetic editing shows promise against chronic hepatitis B in early trials

Study published on epigenetic editing for hepatitis B

1 Sep 21 · 2d ago · 1 article · 2 posts · 3 sources · development 1 of 1

nChroma Bio and institutes in Milan published findings in Nature Biomedical Engineering showing that epigenetic editing—using chemical tags rather than DNA cuts—can shut down hepatitis B viral gene activity. Preclinical tests in human liver cells and mice showed promising efficacy, with only minimal and temporary side effects in primate testing.

Study published on epigenetic editing for hepatitis B
nature.com

“The efficacy of a single injection was "quite impressive". This "is really where we need to go to end up being able to address this pandemic of HBV around the world".”

John Tavis

nChroma Bio Biotechnology firm developing CRMA-1001Angelo Lombardo Molecular biologist, San Raffaele Telethon Institute; nChroma Bio co-founderJohn Tavis Molecular virologist, Saint Louis UniversityFabien Zoulim Virologist and clinical hepatologist, University of Lyon

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1Study published on epigenetic editing for…
Sep 21Sep 22yesterdaynow · 5:05 AM ET

What was reported 1 claim about this development

  1. 1 outlet 'Epigenetic' editing is here: gene-tagging technique banishes hepatitis B virus

    first by Nature News, 3d ago

All 1 developments of Epigenetic editing shows promise against chronic hepatitis… →

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