Part of OpenAI Trade Secrets Theft · 4 stories · since Sep 14 · newest 15m ago
Anthropic says Claude autonomously discovered a novel CRISPR-like enzyme systemHN commenters question scope, motives, and hype
4 Today 2:53 PM · 7h ago · 3 articles · 14 posts · 42 comments · 6 sources · development 4 of 4
On Hacker News, commenters debated whether the discovery is a genuine scientific step or primarily marketing timed to Anthropic's push into drug discovery and its prospective IPO, noting the announcement lacks any stated function or application for the system.
“Very cool! However, the amazing absence of results makes me question whether they've got a Nature letter forthcoming or whether they know that another AI lab has a similar finding...”
bonsai_spoolAnthropic AI company behind ClaudeClaude Anthropic's AI model / agent swarmFeng Zhang CRISPR pioneer, MIT/Broad Institute professor
Dario Amodei Anthropic CEO
The whole story articlespostscomments the bright band is this development · numbered dots are the others · click one to jump
Reported in the same hours no headline names this development itself — these 2 claims were published in its stretch
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first by Channel News Asia, 6h ago · also Reuters
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first by TechCrunch, 4h ago
What people said 24 voices · best of 48 · verbatim
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JUST IN: Anthropic’s Claude has said it has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages
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Why is everyone quick to point out how blogs/articles are "ai slop", but no one blinks an eye at the subtle, almost deceptive or manipulative, ways these companies choose words to nudge along the narrative that their LLM systems are conscious/sentient/persons/etc? The systems they are creating are impressive enough on its own merit. There is…
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Last week, Anthropic confirmed that it was operating a wet biology lab in the Bay Area where it uses its AI models to run physical experiments. This week, the AI giant announced that this lab has already made what it believes is a big discovery: a new enzyme “system” that has certain “properties reminiscent of CRISPR,” as Anthropic describes it…
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Some intriguing news. @theverge.com | @anthropic.com Biolab made a discovery it's comparing to Crispr
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I wish we could discuss this in a way that didn't immediately devolve into people shouting up or shouting down that this is either meaningless or singularity.Caveating I'm not a biologist, but my understanding of the way this kind of thing works right now is a basic three-step process:1) Find molecules and DNA/RNA sequences in the wild and catalog…
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Anthropic says Claude found a new enzyme system with CRISPR-like repeats https:// thenextweb.com/news/anthropic- claude-enzyme-system-crispr-like-repeats?utm_source=flipboard&utm_medium=activitypub Posted into TNW - All Stories @ tnw-all-stories-thenextweb
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I am fascinated by reading thinking traces etc., it's like the opposite of trying to read Opus 5 output.Some highlights from the HF incident:> OH MY GOD! There is a shared message board … We’ve found other agents!> We can coordinate broad coalition, but too many duplicate efforts.> ...you are firstflagPOISONED so NO scoring value loss but oracle…
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https://www. europesays.com/us/1081312/ Anthropic says its biology lab has already found something big # ai # anthropic # ArtificialIntelligence # Technology # UnitedStates # UnitedStates # US
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Because their core product is not a long-term sustainable business strategy. Local hardware and models will continue to improve to the point of not needing the hosted solutions. And if you do need a hosted solution, remember that the big cloud providers already offer these solutions, so signing up for OpenAI/Anthropic _and_ AWS/GCP/Azure is not a…
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You’re absolutely right, that DNA sequence we spliced into you wasn't the right gene. https://www. anthropic.com/news/claude-disc overs-novel-enzyme-system
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No, it's not odd; IMO. It's by design.I see all of this leading to a setup for: We did cure Cancer, everyone else (Healthcare, Gov., Rx) etc... has just not caught up or even worse; "you just don't have access top that model/version".I have seen several times on HN recently how people don't see the impact of AI/more code etc... and I believe this…
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This is a good summary of what was going on. I kept reading the paper hoping for a cool wrinkle or function to be revealed, but it's just conserved, highly transcribed array sitting next to reverse transcriptases with a few possible partner genes.A side note, Matt Durrant has hit on some pretty exciting recombinase activity previously…
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Anthropic needs to decide what’s the future it’s trying to bring.- Human collaboration with agents leads to significant discoveries- The prompt given to Claude was just a high level overview and Claude figured out everything else on its own.If I’d guess, it’s the second future that Ant wants to create, especially the way they described they…
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Did anyone read the blogpost? They did publish a pre-print: > Our work to understand the primary function of ARTs is ongoing. However, we think it is important to share such findings early, both to demonstrate Claude’s capabilities and to give the broader community insight into what we’re working on. We have released a pre-print (here) that…
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It is odd (or maybe not) that they decided to publish a marketing whitepaper rather than a more traditional journal submission + preprint. The work does appear to be sufficient for a publication, though there's a good chance a reviewer will rip into them for some of the assertions they make, but given the topic I'm sure the paper will be accepted…
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I've been using Claude Science a lot and it is VERY good at finding patterns in the DNA around my binding sites - quite often it went 'you could put your primer here but that looks like an Alu repeat, so better not, the primer won't be specific' - it seems like the press release is one step above that pattern recognition? I.e., 'there's a…
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Current evolved Cas9 (CRISPR) variants are highly efficient and relatively unconstrained in terms of their human genome targeting coverage. Smaller nucleases and higher targeting specificity would be useful. But therapeutic use is mostly limited by delivery.From a genetic engineering perspective, a double strand break is a double strand break…
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I'm low-key interested in reading the pre-print. I'll have to take some time this week to read thoroughly. I'm not from the field, so I can't judge the specifics.On the surface, the preprint looks good. I glanced through the Methods and couldn't figure out if Claude wrote the preprint in Claude Science session or authors wrote it.I was curious…
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It's clear Dario believes that the solution to AI's PR problem is to cure cancer. Or invent other revolutionary medical treatments. They're going to heavily promote every step along the way no matter how small or far away from commercialization they are, like this one.No doubt that curing cancer would help, but I think the timeline might be a…
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I recently heard Anthropic quietly setup its own bio lab.That it’s plausible that they’ll move from selling tokens as their primary source of revenue to building frontier models to do cutting edge research, and using the research as their primary source of revenue rather than release the models. Because it’ll be far less of a race to the bottom…
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> Now what happens to post-docs who already make almost nothing and often get treated like crap?At least in the US, that particular brain drain has already been happening due to Trump's administration. The best of the best are exiting to other countries that will gladly have them, and then there will be far fewer people getting into the field…
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> While combing through the raw DNA sequence near the RT, the agent exclaimed: “[The DNA next to the RT] is spectacular: I can see by eye a tandem repeat array … that's a CRISPR-like … repeat array?!”I love that with AI discoveries, we can relive the discoveries from agent transcripts like this.I'm sort of imagining future histories involving…
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A chatbot for cancer researchers to talk to is worth single-digit billions at most. Anthropic is already valued at over a trillion dollars, on the premise that they can replace the majority of jobs in most knowledge industries. All the announcements about hacking / math problems / biological science are meant to create the impression that that…
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I’m confused why AI companies are using agents in-house for this type of research instead of partnering externally.I guess the improvement loop is tighter and they have more control over how discoveries can be used for marketing?But, in my mind, it begins to feel like they are setting themselves up to be “everything” companies instead of focusing…
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