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Nature Study: Human Brain Purges Billions of Genetically Flawed Neurons at Birth

Nature publishes human neuron quality-control study

1 Oct 28 · 11d ago · 2 articles · 1 source · development 1 of 3

Researchers led by Diane Shao report sequencing 2,357 single neurons from brains ranging from 14-week fetuses to nonagenarians, finding that roughly 26% of prenatal cortical neurons carry widespread copy-number variations versus about 6% after birth.

Nature publishes human neuron quality-control study
nature.com

“It suggests that the neurons that survive may be the ones that have kept the most intact genomes during development”

Christos Proukakis, Neurologist, University College London · rss ↗

Diane Shao Paediatric neurogeneticist, Boston Children's HospitalChristopher A. Walsh Study co-authorChristos Proukakis Neurologist, University College London

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