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Israeli study links GLP-1 drugs to rare brain disorder from vitamin B1 deficiency

Study explains vitamin B1 deficiency mechanism in GLP-1 users

1 Sep 11 · 13d ago · 2 articles · 2 sources · development 1 of 2

The research details how GLP-1 drugs slow digestion and reduce appetite, potentially leading to inadequate nutrition and vitamin B1 deficiency. Most patients with Wernicke encephalopathy experienced gastrointestinal issues including weight loss, vomiting, loss of appetite or malnutrition. Only two of 15 patients exhibited the signature triad of WE symptoms—altered mental state, trouble walking, and lack of eye movement control—making the condition difficult to diagnose.

Study explains vitamin B1 deficiency mechanism in GLP-1 users
Fox News

“GLP-1s work by slowing down digestion, making us feel full for longer. The resulting decrease in appetite and food intake can lead to inadequate nutrition, including a deficiency in vitamin B1, also known as thiamine.”

NY Post reporting on study findings

Israeli research team Study authorsDr. Karthik Achari Chicago-based clinician, PepMD founder

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Peak 6 pieces in 3h at Sep 15, 11 AM; 16 pieces over 13 days (14 articles · 2 posts) Sep 11, 11 AM — 2 pieces · 2 articles — Google News 1, Newswires 1Sep 11, 2 PM — quietSep 11, 5 PM — quietSep 11, 8 PM — quietSep 11, 11 PM — quietSep 12, 2 AM — quietSep 12, 5 AM — quietSep 12, 8 AM — quietSep 12, 11 AM — 1 piece · 1 article — Google News 1Sep 12, 2 PM — 1 piece · 1 article — Google News 1Sep 12, 5 PM — quietSep 12, 8 PM — quietSep 12, 11 PM — quietSep 13, 2 AM — quietSep 13, 5 AM — quietSep 13, 8 AM — quietSep 13, 11 AM — 2 pieces · 2 articles — Google News 1, Newswires 1Sep 13, 2 PM — quietSep 13, 5 PM — quietSep 13, 8 PM — quietSep 13, 11 PM — quietSep 14, 2 AM — quietSep 14, 5 AM — quietSep 14, 8 AM — quietSep 14, 11 AM — 2 pieces · 2 articles — Google News 1, Newswires 1Sep 14, 2 PM — quietSep 14, 5 PM — quietSep 14, 8 PM — 1 piece · 1 post — Mastodon 1Sep 14, 11 PM — quietSep 15, 2 AM — quietSep 15, 5 AM — quietSep 15, 8 AM — quietSep 15, 11 AM — 6 pieces · 5 articles · 1 post — Google News 5, Mastodon 1Sep 15, 2 PM — quietSep 15, 5 PM — quietSep 15, 8 PM — quietSep 15, 11 PM — quietSep 16, 2 AM — 1 piece · 1 article — Google News 1Sep 16, 5 AM — quietSep 16, 8 AM — quietSep 16, 11 AM — quietSep 16, 2 PM — quietSep 16, 5 PM — quietSep 16, 8 PM — quietSep 16, 11 PM — quietSep 17, 2 AM — quietSep 17, 5 AM — quietSep 17, 8 AM — quietSep 17, 11 AM — quietSep 17, 2 PM — quietSep 17, 5 PM — quietSep 17, 8 PM — quietSep 17, 11 PM — quietSep 18, 2 AM — quietSep 18, 5 AM — quietSep 18, 8 AM — quietSep 18, 11 AM — quietSep 18, 2 PM — quietSep 18, 5 PM — quietSep 18, 8 PM — quietSep 18, 11 PM — quietSep 19, 2 AM — quietSep 19, 5 AM — quietSep 19, 8 AM — quietSep 19, 11 AM — quietSep 19, 2 PM — quietSep 19, 5 PM — quietSep 19, 8 PM — quietSep 19, 11 PM — quietSep 20, 2 AM — quietSep 20, 5 AM — quietSep 20, 8 AM — quietSep 20, 11 AM — quietSep 20, 2 PM — quietSep 20, 5 PM — quietSep 20, 8 PM — quietSep 20, 11 PM — quietSep 21, 2 AM — quietSep 21, 5 AM — quietSep 21, 8 AM — quietSep 21, 11 AM — quietSep 21, 2 PM — quietSep 21, 5 PM — quietSep 21, 8 PM — quietSep 21, 11 PM — quietSep 22, 2 AM — quietSep 22, 5 AM — quietSep 22, 8 AM — quietSep 22, 11 AM — quietSep 22, 2 PM — quietSep 22, 5 PM — quietSep 22, 8 PM — quietSep 22, 11 PM — quietYesterday, 2 AM — quietYesterday, 5 AM — quietYesterday, 8 AM — quietYesterday, 11 AM — quietYesterday, 2 PM — quietYesterday, 5 PM — quietYesterday, 8 PM — quietYesterday, 11 PM — quietToday, 2 AM — quietToday, 5 AM — quiet ◂ 1 earlier2
2Clinician contextualizes rarity of cases…
Sep 12Sep 13Sep 14Sep 15Sep 16Sep 17Sep 18Sep 19Sep 20Sep 21Sep 22now · 8:52 AM ET

What was reported 2 claims about this development

  1. 2 outlets GLP-1-driven vitamin deficiency linked to rare brain disorder: Study

    first by The Hill, 9d ago · also NewsNation

  2. 2 outlets Popular GLP-1 drugs may trigger a rare, life-threatening brain disorder: study

    first by NY Post, 12d ago · also New York Post

All 2 developments of Israeli study links GLP-1 drugs to rare brain disorder from… →

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