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Israeli study links GLP-1 drugs to rare brain disorder from vitamin B1 deficiency

Clinician contextualizes rarity of cases relative to GLP-1 user population

2 Sep 13 1:00 PM · 10d ago · 5 articles · 2 sources · development 2 of 2

Dr. Karthik Achari, a Chicago-based clinician not involved in the study, told Fox News that the 15 cases identified must be viewed in perspective against millions of people taking GLP-1 medications. He explained the mechanism: the drugs reduce appetite but not the body's nutritional requirements, and certain patients—those with persistent nausea, rapid weight loss on minimal food intake, prior bariatric surgery, or heavy alcohol use—face higher risk.

Clinician contextualizes rarity of cases relative to GLP-1 user population
Fox News

“Researchers went through adverse event reports and the medical literature and found a small number of cases, 15, of Wernicke encephalopathy in people taking GLP-1 drugs. That's out of millions of people on these medications. So this is rare.”

Dr. Karthik Achari

Israeli research team Study authorsDr. Karthik Achari Chicago-based clinician, PepMD founder

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2Clinician contextualizes rarity of cases…
Sep 12Sep 13Sep 14Sep 15Sep 16Sep 17Sep 18Sep 19Sep 20Sep 21Sep 22now · 8:52 AM ET

What was reported 1 claim about this development

  1. 1 outlet Study Flags Rare Neurological Disorder in Patients Taking GLP-1 Drugs

    first by NTD News, 8d ago

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