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Researchers identify molecular pathway linking cold exposure to extended lifespan

Nature study identifies BH2 pathway linking cold to longevity

1 Oct 29 · 9d ago · 3 articles · 1 post · 3 sources · development 1 of 2

Researchers from the University of Cologne published findings in Nature showing that moderately cold temperatures (15°C/59°F) trigger production of an enzyme called CAT-4 in muscle tissue, which stimulates production of the metabolite BH2. BH2 is then transported to other tissues where it supports protein homeostasis and tissue health.

Nature study identifies BH2 pathway linking cold to longevity
sciencealert.com

“We are excited to show that mildly cold temperatures trigger significant production of a specific metabolite, BH2, which is synthesized, stored, and subsequently released by muscle tissue.”

David Vilchez

David Vilchez Molecular biologist, University of CologneUniversity of Cologne Research institution

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Peak 8 pieces in 3h at Oct 29, 8 PM; 10 pieces over 10 days (7 articles · 3 posts) Oct 29, 8 PM — 8 pieces · 7 articles · 1 post — Google News 6, Mastodon 1, Newswires 1Oct 29, 11 PM — quietOct 30, 2 AM — quietOct 30, 5 AM — quietOct 30, 8 AM — quietOct 30, 11 AM — quietOct 30, 2 PM — 2 pieces · 2 posts — Hacker News 1, Mastodon 1Oct 30, 5 PM — quietOct 30, 8 PM — quietOct 30, 11 PM — quietOct 31, 2 AM — quietOct 31, 5 AM — quietOct 31, 8 AM — quietOct 31, 11 AM — quietOct 31, 2 PM — quietOct 31, 5 PM — quietOct 31, 8 PM — quietOct 31, 11 PM — quietNov 1, 1 AM — quietNov 1, 4 AM — quietNov 1, 7 AM — quietNov 1, 10 AM — quietNov 1, 1 PM — quietNov 1, 4 PM — quietNov 1, 7 PM — quietNov 1, 10 PM — quietNov 2, 1 AM — quietNov 2, 4 AM — quietNov 2, 7 AM — quietNov 2, 10 AM — quietNov 2, 1 PM — quietNov 2, 4 PM — quietNov 2, 7 PM — quietNov 2, 10 PM — quietNov 3, 1 AM — quietNov 3, 4 AM — quietNov 3, 7 AM — quietNov 3, 10 AM — quietNov 3, 1 PM — quietNov 3, 4 PM — quietNov 3, 7 PM — quietNov 3, 10 PM — quietNov 4, 1 AM — quietNov 4, 4 AM — quietNov 4, 7 AM — quietNov 4, 10 AM — quietNov 4, 1 PM — quietNov 4, 4 PM — quietNov 4, 7 PM — quietNov 4, 10 PM — quietNov 5, 1 AM — quietNov 5, 4 AM — quietNov 5, 7 AM — quietNov 5, 10 AM — quietNov 5, 1 PM — quietNov 5, 4 PM — quietNov 5, 7 PM — quietNov 5, 10 PM — quietNov 6, 1 AM — quietNov 6, 4 AM — quietNov 6, 7 AM — quietNov 6, 10 AM — quietNov 6, 1 PM — quietNov 6, 4 PM — quietNov 6, 7 PM — quietNov 6, 10 PM — quietYesterday, 1 AM — quietYesterday, 4 AM — quietYesterday, 7 AM — quietYesterday, 10 AM — quietYesterday, 1 PM — quietYesterday, 4 PM — quietYesterday, 7 PM — quietYesterday, 10 PM — quietToday, 1 AM — quietToday, 4 AM — quietToday, 7 AM — quietToday, 10 AM — quietToday, 1 PM — quiet 12
1Nature study identifies BH2 pathway…2Pathway shows potential for treating…
Oct 30Oct 31Nov 1Nov 2Nov 3Nov 4Nov 5Nov 6yesterdaynow · 2:40 PM ET

What was reported 1 claim about this development

  1. 3 outlets How cold extends worms’ lifespan: the BH2 pathway

    first by UA.NEWS, 9d ago · also ScienceAlert, Yahoo

    1 more headline

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