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Researchers identify molecular pathway linking cold exposure to extended lifespan

Pathway shows potential for treating protein-folding diseases

2 Oct 30 · 9d ago · 1 post · 1 source · development 2 of 2

The identified BH2 pathway also boosted healthy protein homeostasis in a worm model of Huntington's disease, suppressing harmful protein aggregation and suggesting that targeting muscle tissue could provide organism-wide protection.

Pathway shows potential for treating protein-folding diseases
sciencealert.com

“These findings suggest that specifically targeting a single tissue, such as muscle, could provide organism-wide protection.”

David Vilchez

David Vilchez Molecular biologist, University of CologneUniversity of Cologne Research institution

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1Nature study identifies BH2 pathway…2Pathway shows potential for treating…
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