HealthQuiet 36d · day 37
Colorectal tumors damage nerves before chemotherapy, UT research shows
A discovery that cancer itself—not just treatment—causes nerve damage could reshape how doctors approach peripheral neuropathy in colorectal cancer.
What to know
- Colorectal cancer tumors themselves—not just chemotherapy—can damage peripheral nerves in preclinical models.
- The finding challenges the prevailing assumption that cancer-related neuropathy is solely a side effect of treatment.
- Tumors were linked to inflammation, nerve fiber loss, and impaired electrical signaling before chemotherapy began.
“Colorectal tumors may begin damaging peripheral nerves before patients receive chemotherapy, challenging the widely held assumption that cancer-related neuropathy is primarily a consequence of treatment.”
University of Texas MD Anderson Cancer Center · Mastodon / ScienceMag
University of Texas MD Anderson Cancer Center Research institution
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