HealthQuiet 29d · day 30
Nanoparticles reverse Alzheimer's in mice by converting brain cells to neurons
A South Carolina research team showed engineered nanoparticles can regenerate neurons and restore cognition in Alzheimer's disease models.
What to know
- Engineered nanoparticles composed of a cage structure with antibodies converted brain support cells into functioning neurons in mice with Alzheimer's disease.
- The treatment reversed memory loss and restored neural circuits in animal models, and regenerated neurons in human brain organoids in vitro.
- Existing Alzheimer's treatments only slow progression; this work suggests a potential path to reversing cognitive decline.
“A drug made up of a cage of nanoparticles and antibodies created neurons from another type of brain cell, which relieved symptoms of Alzheimer's disease in mice”
New Scientist · New Scientist
South Carolina research team Research group
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