ScienceQuiet 18d · day 22
Scientists map protein interactions linked to profound autism
Research identifies key molecular pathways that could lead to new drug treatments for severe autism.
What to know
- UC San Francisco researchers have mapped over 1,000 protein interactions from autism risk genes, filling a crucial gap in understanding how mutations cause profound autism.
- The molecular atlas, published in Science, offers new targets for drug development for people with severe intellectual disability and complex medical needs.
- Experts and patient advocacy leaders hail the work as a breakthrough that clarifies the path from genetic discovery to treatment.
“This is the kind of scientific advance we have been waiting for and praying for. There's still a lot of work ahead, [but] this paper makes the path from genetic discovery to treatment much clearer.”
Alison Singer, President, Autism Science Foundation · NPR News
UC San Francisco research team Researchers who conducted the study
Nevan Krogan Director, Quantitative Biosciences Institute at UCSFDr. Daniel Geschwind Professor of human genetics, neurology, and psychiatry at UCLA
Alison Singer President, Autism Science Foundation
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