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ScienceQuiet 3d · day 8

Scientists implant human brain organoids into mice to study neurodevelopment

Researchers use human-derived neural tissue in rodent brains to analyze how human neurons develop and form circuits.

newest coverage 2d agosummary written 6d ago5 pieces3 likes & upvotes1 comments NewswiresMastodonGoogle NewsHacker News

What to know

  • Researchers implanted human-derived brain organoids into mice to study how human neurons develop and form functional circuits.
  • The technique, called developmental xenocortication, allows analysis of human neurodevelopment at both circuit and behavioral levels in living animals.
  • The study was published in Nature on September 16, 2026, by a team including Sergiu P. Pașca and Karl Deisseroth.

“Xenocortication with human neurons enables circuit- and behaviour-level analysis of neurodevelopment in mice.”

Nature · Nature News ↗

Sergiu P. Pașca Lead researcherKarl Deisseroth Co-author

How it unfolded 1 development · click the chart to see its coverage articlesposts

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  1. 1

    Nature publishes xenocortication study using human organoids in mice

    A research team led by Sergiu P. Pașca and others published a study in Nature describing developmental xenocortication—implanting human-derived brain organoids into mice brains. The technique enables circuit- and behavior-level analysis of human neurodevelopment in a living animal model.

    1. 2 outlets first by Nature, 7d ago · also Nature News · read ↗