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HealthQuiet 3d · day 7

Swedish trial finds numbing IUD lining cuts insertion pain

A double-blind trial of intrauterine mepivacaine before IUD placement lowered reported pain scores and increased how many patients called the pain tolerable.

What to know

  • A Swedish double-blind trial of 370 patients found instilling mepivacaine into the uterus before IUD insertion cut pain scores from 58.6mm to 43.8mm on a 100-point scale.
  • 98.3% of mepivacaine recipients found pain tolerable versus 91.4% with placebo, with a number needed to treat of 15 for one additional patient to report tolerable pain.
  • The method does not address pain from other parts of the procedure, such as speculum or tenaculum use, according to an outside ob/gyn.
  • Findings arrive amid rising patient reports of IUD insertion pain on social media and calls from the CDC and ACOG for better clinician counseling and pain management options.

“The strategy these authors were investigating to manage pain would have no impact on speculum or tenaculum placement and it was not asked about during the assessment”

Nikki Zite, Ob/gyn commentator · MedPage Today ↗ · Sep 17

Karin Elgemark Lead study author, Karolinska InstitutetNikki Zite Ob/gyn, University of Tennessee Graduate School of MedicineCDC Public health agencyAmerican College of Obstetricians and Gynecologists Professional medical body

Swedish trial finds numbing IUD lining cuts insertion pain
MedPage Today

How it unfolded 3 developments, newest first · click a bar or a number to jump articlesposts

Peak 3 pieces in two hours at Sep 18, 4 PM; 8 pieces over 7 days (7 articles · 1 post) Sep 17, 4 AM — 2 pieces · 2 articles — Google News 2Sep 17, 6 AM — quietSep 17, 8 AM — quietSep 17, 10 AM — 2 pieces · 2 articles — Google News 2Sep 17, 12 PM — quietSep 17, 2 PM — quietSep 17, 4 PM — quietSep 17, 6 PM — quietSep 17, 8 PM — quietSep 17, 10 PM — quietSep 18, 12 AM — quietSep 18, 2 AM — quietSep 18, 4 AM — quietSep 18, 6 AM — quietSep 18, 8 AM — quietSep 18, 10 AM — quietSep 18, 12 PM — quietSep 18, 2 PM — quietSep 18, 4 PM — 3 pieces · 3 articles — Google News 2, Newswires 1Sep 18, 6 PM — quietSep 18, 8 PM — quietSep 18, 10 PM — quietSep 19, 12 AM — quietSep 19, 2 AM — quietSep 19, 4 AM — quietSep 19, 6 AM — quietSep 19, 8 AM — quietSep 19, 10 AM — quietSep 19, 12 PM — quietSep 19, 2 PM — quietSep 19, 4 PM — quietSep 19, 6 PM — quietSep 19, 8 PM — quietSep 19, 10 PM — quietSep 20, 12 AM — quietSep 20, 2 AM — quietSep 20, 4 AM — quietSep 20, 6 AM — quietSep 20, 8 AM — quietSep 20, 10 AM — quietSep 20, 12 PM — quietSep 20, 2 PM — quietSep 20, 4 PM — quietSep 20, 6 PM — quietSep 20, 8 PM — quietSep 20, 10 PM — 1 piece · 1 post — Mastodon 1Sep 21, 12 AM — quietSep 21, 2 AM — quietSep 21, 4 AM — quietSep 21, 6 AM — quietSep 21, 8 AM — quietSep 21, 10 AM — quietSep 21, 12 PM — quietSep 21, 2 PM — quietSep 21, 4 PM — quietSep 21, 6 PM — quietSep 21, 8 PM — quietSep 21, 10 PM — quietSep 22, 12 AM — quietSep 22, 2 AM — quietSep 22, 4 AM — quietSep 22, 6 AM — quietSep 22, 8 AM — quietSep 22, 10 AM — quietSep 22, 12 PM — quietSep 22, 2 PM — quietSep 22, 4 PM — quietSep 22, 6 PM — quietSep 22, 8 PM — quietSep 22, 10 PM — quietYesterday, 12 AM — quietYesterday, 2 AM — quietYesterday, 4 AM — quietYesterday, 6 AM — quietYesterday, 8 AM — quietYesterday, 10 AM — quietYesterday, 12 PM — quietYesterday, 2 PM — quietYesterday, 4 PM — quietYesterday, 6 PM — quietYesterday, 8 PM — quietYesterday, 10 PM — quietToday, 12 AM — quiet 123
Sep 18Sep 19Sep 20Sep 21Sep 22yesterdaynow · 2:07 AM ET
  1. 3

    Science communicators amplify the findings on social media

    A science media outreach account shares the study via a scimex.org writeup, describing the anesthetic as well tolerated and effective at reducing IUD insertion pain.

    “An anesthetic squirted into the uterus via the cervix is well tolerated and greatly reduces the pain involved with getting an intrauterine birth control device…”
    — AusSMC@aus.social
    • AusSMC@aus.social

      👩‍⚕️An anesthetic squirted into the uterus via the cervix is well tolerated and greatly reduces the pain involved with getting an intrauterine birth control device, commonly referred to as an IUD ✨Follow the link for more information on this story✨ https://www. scimex.org/newsfeed/local-anes…

      AusSMC@aus.socialMastodon3d ago2▲view on Mastodon ↗
  2. 1 day quiet
  3. 2

    Yahoo Health frames method as 'needle-free anesthetic' breakthrough

    Syndicated coverage of the same trial highlights that the anesthetic is administered via a catheter rather than an injection, emphasizing it as a needle-free option for reducing IUD insertion pain.

    “Considering the frequency of IUD placements worldwide, even modest reductions in the proportion of individuals experiencing intolerable pain may have important clinical implications…”
    — Karin Elgemark, Study lead author, Karolinska Institutet · source
    1. first by Yahoo Health, 5d ago

  4. background

    MedPage Today details the mepivacaine trial's results and limits — The trial of 370 nulliparous patients aged 18-31 at 11 Swedish clinics found mean pain scores of 43.8mm with mepivacaine versus 58.6mm with placebo (P<0.001), and 98.3% versus 91.4% reporting tolerable pain; a commentator noted the method doesn't address pain from the speculum or tenaculum.

  5. 1

    Outlets report Swedish trial results on IUD pain relief

    News coverage summarizes a JAMA-published Swedish randomized trial finding that a new anesthetic instillation method reduced pain during IUD insertion compared with placebo.

    1. first by MedPage Today, 5d ago

    2. first by Nursing in Practice, 6d ago

      1 more headline
    1 more claim →