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Viking Therapeutics soars 39.5% on obesity drug maintenance trial data

VK2735 showed it could preserve up to 97% of weight loss on reduced dosing, challenging rivals Eli Lilly and Novo Nordisk.

What to know

  • VK2735 maintenance study showed patients on every-other-week dosing retained 97% of weight loss vs. 61% for placebo, with safety comparable to placebo—validating reduced dosing as a competitive advantage.
  • Stock surged 39.5% on the news, approaching 52-week highs, as investors and analysts see Viking challenging Eli Lilly and Novo Nordisk's obesity drug dominance through dosing flexibility and tolerability.
  • The company plans to explore oral formulations and has Phase 3 trials fully enrolled with additional oral Phase 3 initiation expected later in 2026, plus a strong $502M cash position to fund development.

“many investors had assumed Eli Lilly's tirzepatide would thoroughly dominate the GLP-1/GIP category, and that upcoming VK2735 maintenance data could establish adherence as the next major competitive battleground”

Oppenheimer, Equity research · Investing.com ↗

Viking Therapeutics Clinical-stage biopharmaceutical companyEli LillyEli Lilly Obesity drug competitorNovo Nordisk Obesity drug competitorOppenheimer Equity research analyst

Viking Therapeutics soars 39.5% on obesity drug maintenance trial data
Investing.com News

How it unfolded 1 development · click the chart to see its coverage articles

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  1. 1

    Viking stock surges 39.5% on maintenance data release

    VKTX surged 39.5% in pre-open trading, sending shares to $42 and approaching its 52-week high of $43.15, driven entirely by company-specific news rather than broader market movement.

    “In the 12-week maintenance phase, every-other-week dosing preserved up to 97% of prior weight loss and monthly dosing up to 90%, compared with 61% for placebo.”
    — Viking Therapeutics, Company announcement · source
  2. background

    Viking Therapeutics reports VK2735 maintenance study results — The San Diego-based biopharmaceutical company announced positive top-line results from the 12-week maintenance phase of VK2735, showing every-other-week dosing preserved up to 97% of prior weight loss and monthly dosing up to 90%, compared with 61% for placebo, with statistically significant separation and adverse event rates comparable to placebo.

Also covered reported alongside — the timeline has no entry for these yet

  1. first by Investor's Business Daily, 1d ago · also Seeking Alpha, Investing.com News, Barron's, Moomoo

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