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SportsQuiet 37h · day 9

NFL Week 3 picks and predictions: Broncos, Bills, Eagles favored

Experts across major sportsbooks release opening odds and early picks for all 16 Week 3 NFL games.

newest coverage 1d agosummary written 1d ago18 pieces NewswiresGoogle NewsMastodon

What to know

  • Week 3 NFL odds released across major platforms; experts emphasize how quarterback injuries significantly reshape matchup outcomes, particularly Caleb Williams' absence for the Bears and Myles Garrett/Puka Nacua losses for the Rams.
  • Broncos favored over Rams based on Denver's strong home record with Bo Nix and Rams' diminished roster; Bills positioned as AFC favorites following dominant Week 2 wins.
  • Eagles backed over Bears with Jalen Hurts facing backup Tyson Bagent; early-week betting markets show continued movement on totals, reflecting ongoing team evaluation from limited sample size.

“The Eagles catch an important break after working hard to avoid their Titans upset in Week 2. Caleb Williams (hamstring) will be at least be missing this game, pushing the QB matchup highly in the favor of Jalen Hurts vs. rusty backup Tyson Bagent.”

Vinnie Iyer, Sporting News NFL analyst · Sporting News ↗

Vinnie Iyer Sporting News NFL analystMichael Fiddle Yahoo Sports NFL handicapperEric Cohen SportsLine expert

NFL Week 3 picks and predictions: Broncos, Bills, Eagles favored
Yahoo Sports

How it unfolded 8 developments, newest first · click a bar or a number to jump articlesposts

Peak 5 pieces in two hours at Sep 22, 8 AM; 18 pieces over 9 days (16 articles · 2 posts) Sep 15, 2 PM — 1 piece · 1 article — Newswires 1Sep 15, 4 PM — quietSep 15, 6 PM — quietSep 15, 8 PM — quietSep 15, 10 PM — quietSep 16, 12 AM — quietSep 16, 2 AM — quietSep 16, 4 AM — quietSep 16, 6 AM — quietSep 16, 8 AM — quietSep 16, 10 AM — quietSep 16, 12 PM — quietSep 16, 2 PM — quietSep 16, 4 PM — quietSep 16, 6 PM — quietSep 16, 8 PM — quietSep 16, 10 PM — quietSep 17, 12 AM — quietSep 17, 2 AM — quietSep 17, 4 AM — quietSep 17, 6 AM — quietSep 17, 8 AM — quietSep 17, 10 AM — 2 pieces · 2 articles — Newswires 2Sep 17, 12 PM — quietSep 17, 2 PM — quietSep 17, 4 PM — quietSep 17, 6 PM — quietSep 17, 8 PM — quietSep 17, 10 PM — quietSep 18, 12 AM — quietSep 18, 2 AM — quietSep 18, 4 AM — 1 piece · 1 article — Google News 1Sep 18, 6 AM — quietSep 18, 8 AM — quietSep 18, 10 AM — quietSep 18, 12 PM — quietSep 18, 2 PM — quietSep 18, 4 PM — quietSep 18, 6 PM — quietSep 18, 8 PM — quietSep 18, 10 PM — quietSep 19, 12 AM — quietSep 19, 2 AM — quietSep 19, 4 AM — quietSep 19, 6 AM — quietSep 19, 8 AM — quietSep 19, 10 AM — quietSep 19, 12 PM — quietSep 19, 2 PM — quietSep 19, 4 PM — quietSep 19, 6 PM — quietSep 19, 8 PM — quietSep 19, 10 PM — quietSep 20, 12 AM — quietSep 20, 2 AM — quietSep 20, 4 AM — quietSep 20, 6 AM — quietSep 20, 8 AM — quietSep 20, 10 AM — quietSep 20, 12 PM — quietSep 20, 2 PM — quietSep 20, 4 PM — quietSep 20, 6 PM — quietSep 20, 8 PM — 1 piece · 1 article — Newswires 1Sep 20, 10 PM — quietSep 21, 12 AM — quietSep 21, 2 AM — quietSep 21, 4 AM — quietSep 21, 6 AM — quietSep 21, 8 AM — quietSep 21, 10 AM — 3 pieces · 3 articles — Google News 3Sep 21, 12 PM — quietSep 21, 2 PM — quietSep 21, 4 PM — quietSep 21, 6 PM — quietSep 21, 8 PM — quietSep 21, 10 PM — quietSep 22, 12 AM — quietSep 22, 2 AM — quietSep 22, 4 AM — quietSep 22, 6 AM — 1 piece · 1 article — Newswires 1Sep 22, 8 AM — 5 pieces · 4 articles · 1 post — Google News 3, Mastodon 1, Newswires 1Sep 22, 10 AM — quietSep 22, 12 PM — 2 pieces · 2 articles — Newswires 2Sep 22, 2 PM — 2 pieces · 1 article · 1 post — Mastodon 1, Newswires 1Sep 22, 4 PM — quietSep 22, 6 PM — quietSep 22, 8 PM — quietSep 22, 10 PM — quietYesterday, 12 AM — quietYesterday, 2 AM — quietYesterday, 4 AM — quietYesterday, 6 AM — quietYesterday, 8 AM — quietYesterday, 10 AM — quietYesterday, 12 PM — quietYesterday, 2 PM — quietYesterday, 4 PM — quietYesterday, 6 PM — quietYesterday, 8 PM — quietYesterday, 10 PM — quietToday, 12 AM — quietToday, 2 AM — quiet 123–8
Sep 16Sep 17Sep 18Sep 19Sep 20Sep 21Sep 22now · 4:44 AM ET
  1. 8

    CBS Sports finalizes Week 3 betting odds across all platforms

    Brandt Sutton's comprehensive guide to Week 3 NFL betting odds and lines covers spreads for all 16 games, with Packers-Falcons as the Thursday Night Football opener.

    1. 1 outlet Week 3 NFL betting odds, lines, totals, spreads, for all 16 games, including Cowboys-Ravens, Rams-Broncos

      first by CBS Sports, 1d ago

  2. 7

    CBS Sports expert reveals exact score predictions for Week 3

    Ross Kelly and SportsLine expert Eric Cohen provide score predictions for every Week 3 NFL game.

    1. 1 outlet first by CBS Sports, 1d ago · read ↗

    2. 1 outlet NFL Week 3 picks, predictions, score projections for games this week

      first by azcentral.com and The Arizona Republic, 1d ago

  3. 6

    Yahoo Sports handicapper selects two Week 3 wagers to monitor

    Michael Fiddle identifies two early-week bets he favors as Week 3 odds settle across sportsbooks.

    1. 2 outlets College football Week 3 best bets, odds: My favorite wagers

      first by Yahoo Sports, 6d ago · also CBS Sports

      2 more headlines
    2. 1 outlet Early Week 3 NFL bets to make right now: 2 wagers that I like

      first by Yahoo Sports, 1d ago

  4. 5

    Multiple outlets publish Week 3 betting odds and predictions

    CBS Sports, azcentral.com, and other outlets release comprehensive Week 3 NFL odds, lines, spreads, and expert predictions for all 16 games.

    • NFL Week 3 game picks: Odds and expert predictions for every matchup https://www. usatoday.com/story/sports/nfl/ 2026/09/22/nfl-week-3-game-picks-predictions-odds/91811611007/?utm_source=flipboard&utm_medium=activitypub Posted into Sports @ sports-USAToday

      USAToday@flipboard.comMastodon1d agoview on Mastodon ↗
  5. 4

    Yahoo Sports posts Rams-Broncos opening odds for Week 3

    Yahoo Sports releases betting odds for the Week 3 matchup between the Rams and Broncos.

    1. 1 outlet first by Yahoo Sports, 1d ago · read ↗

  6. 3

    Sporting News releases Week 3 picks with emphasis on injury impact

    Vinnie Iyer provides fearless forecasts for all 16 Week 3 matchups, highlighting key injury absences affecting team performance. Notable picks include Broncos over Rams (citing Myles Garrett and Puka Nacua absences for LA), Eagles over Bears (with Caleb Williams sidelined by hamstring injury), and Bills over Chargers. The analysis emphasizes how small sample sizes from Week 2 still leave teams difficult to evaluate.

    “The Rams have lost Myles Garrett for a while and now Puka Nacua is on the shelf, too. Those are significant game-changing pieces who set the critical tone for the defense and offense.”
    — Vinnie Iyer
    1. 1 outlet NFL picks, predictions against the spread Week 3: Broncos buck Rams, Bengals bounce Steelers

      first by Sporting News, 1d ago

  7. 2

    Week 3 NFL odds released across major sportsbooks

    Yahoo Sports publishes the full list of opening spreads for Week 3, with lines available on platforms including FanDuel and BetMGM.

    1. 2 outlets 2026 NFL Week 3 odds, betting: Full list of Week 3 spreads

      first by Yahoo Sports, 3d ago · also SportsLine

      1 more headline
  8. 4 days quiet
  9. 1

    Handicapper identifies high-scoring trend driving Week 2 over bets

    Michael Fiddle of Yahoo Sports notes that Week 1 saw a record 791 total points scored since the NFL-AFL merger in 1966, attributing the spike to deep QB talent and innovative playcalling. He backs the over in multiple Week 2 totals markets.

    1. 1 outlet Early Week 2 NFL bets to make right now: 3 totals that I like

      first by Yahoo Sports, 8d ago

Also covered reported alongside — the timeline has no entry for these yet

  1. 1 outlet Early bets for NFL Week 3: Games that drew our attention once odds came out

    first by ESPN, 2d ago

    1 more headline