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SportsQuiet 5d · day 12

NFL Week 2 odds and picks: Seahawks, Buccaneers favored by computer model

Betting analysts and computer simulations release predictions for the league's second week of games.

Part of a larger narrative

2026 NFL Season Injury Wave

5 stories · since Sep 3 · newest 1d ago — Key players suffer significant injuries in the opening weeks of the 2026 NFL season, disrupting rosters and reshaping early competitive balance.

  1. Cowboys host Commanders in Week 2 after each team's Week 1 loss
  2. Giants QB Jaxson Dart injures left knee vs. Rams; MCL feared, Winston in
  3. NFL Week 2 odds and picks: Seahawks, Buccaneers favored by computer modelyou are here
  4. A.J. Brown exits Patriots debut with ankle injury vs. Seahawks
  5. 2026 NFL season opens Wednesday with Seahawks-Patriots rematch

What to know

  • Week 1 produced major upsets (Cardinals beat Chargers 26-14) that influenced Week 2 oddsmakers, with six games carrying spreads of at least a touchdown.
  • SportsLine's computer model, which has a 53-39 record on top-rated picks since 2024, backs the Seahawks at -4.5 over Arizona and Buccaneers at -8.5 over Cleveland, both forecasted to cover in over 60% of 10,000 simulations.
  • The 49ers are 12.5-point home favorites over Miami—the biggest spread of the young season—while the Rams are 7-point favorites over the Giants on Monday Night Football.

“Perhaps no team looked worse in Week 1 than Cleveland, as the Browns allowed 34 points to Jacksonville, saw Deshaun Watson get sacked five times, and only managed a garbage-time touchdown versus backups.”

CBS Sports · CBS Sports ↗ · Sep 15, 8:36 AM

SportsLine Sports betting prediction model providerJosh AllenJosh Allen Buffalo Bills quarterbackCaleb WilliamsCaleb Williams Chicago Bears quarterback

NFL Week 2 odds and picks: Seahawks, Buccaneers favored by computer model
Yahoo Sports

How it unfolded 6 developments, newest first · click a bar or a number to jump articlesposts

Peak 80 pieces in 3h at Sep 17, 10 PM; 451 pieces over 12 days (319 articles · 72 posts · 60 comments) Sep 12, 10 AM — 1 piece · 1 post — Mastodon 1Sep 12, 1 PM — quietSep 12, 4 PM — quietSep 12, 7 PM — quietSep 12, 10 PM — quietSep 13, 1 AM — quietSep 13, 4 AM — quietSep 13, 7 AM — quietSep 13, 10 AM — 2 pieces · 1 article · 1 post — Newswires 1, X 1Sep 13, 1 PM — 3 pieces · 3 posts — Reddit 3Sep 13, 4 PM — quietSep 13, 7 PM — 2 pieces · 1 article · 1 post — Mastodon 1, Newswires 1Sep 13, 10 PM — quietSep 14, 1 AM — 7 pieces · 5 articles · 2 posts — Newswires 4, Mastodon 2, Google News 1Sep 14, 4 AM — 3 pieces · 1 article · 2 posts — Bluesky 1, Mastodon 1, Newswires 1Sep 14, 7 AM — 3 pieces · 3 articles — Newswires 3Sep 14, 10 AM — 4 pieces · 4 articles — Google News 3, Newswires 1Sep 14, 1 PM — 1 piece · 1 post — Bluesky 1Sep 14, 4 PM — quietSep 14, 7 PM — quietSep 14, 10 PM — quietSep 15, 1 AM — quietSep 15, 4 AM — quietSep 15, 7 AM — 8 pieces · 5 articles · 3 posts — Newswires 5, Mastodon 3Sep 15, 10 AM — 4 pieces · 4 articles — Google News 3, Newswires 1Sep 15, 1 PM — 2 pieces · 2 articles — Newswires 2Sep 15, 4 PM — quietSep 15, 7 PM — 2 pieces · 2 articles — Newswires 2Sep 15, 10 PM — quietSep 16, 1 AM — quietSep 16, 4 AM — 3 pieces · 1 article · 2 posts — Mastodon 2, Newswires 1Sep 16, 7 AM — 11 pieces · 6 articles · 5 posts — Newswires 6, Mastodon 5Sep 16, 10 AM — 5 pieces · 5 articles — Newswires 3, Google News 2Sep 16, 1 PM — 7 pieces · 6 articles · 1 post — Google News 4, Newswires 2, Reddit 1Sep 16, 4 PM — 4 pieces · 2 articles · 2 posts — Newswires 2, Mastodon 1, Reddit 1Sep 16, 7 PM — 1 piece · 1 article — Newswires 1Sep 16, 10 PM — 4 pieces · 4 articles — Newswires 4Sep 17, 1 AM — 3 pieces · 1 article · 2 posts — Mastodon 3Sep 17, 4 AM — 22 pieces · 18 articles · 4 posts — Newswires 13, Google News 5, Mastodon 4Sep 17, 7 AM — 52 pieces · 48 articles · 4 posts — Google News 32, Newswires 16, Mastodon 4Sep 17, 10 AM — 16 pieces · 14 articles · 2 posts — Newswires 14, Mastodon 2Sep 17, 1 PM — 25 pieces · 23 articles · 2 posts — Newswires 12, Google News 11, Mastodon 2Sep 17, 4 PM — 46 pieces · 39 articles · 7 posts — Newswires 28, Google News 11, Mastodon 3, +3 moreSep 17, 7 PM — 51 pieces · 29 articles · 10 posts · 12 comments — Newswires 21, Reddit 16, Google News 8, +2 moreSep 17, 10 PM — 80 pieces · 48 articles · 5 posts · 27 comments — Newswires 35, Reddit 28, Google News 13, +2 moreSep 18, 1 AM — 32 pieces · 21 articles · 6 posts · 5 comments — Newswires 20, Mastodon 6, Reddit 5, +1 moreSep 18, 4 AM — 11 pieces · 9 articles · 1 post · 1 comment — Newswires 9, Mastodon 1, Reddit 1Sep 18, 7 AM — 13 pieces · 11 articles · 1 post · 1 comment — Newswires 11, Reddit 2Sep 18, 10 AM — 8 pieces · 4 articles · 1 post · 3 comments — Reddit 4, Newswires 4Sep 18, 1 PM — 8 pieces · 2 posts · 6 comments — Reddit 7, Mastodon 1Sep 18, 4 PM — quietSep 18, 7 PM — 3 pieces · 3 comments — Reddit 3Sep 18, 10 PM — quietSep 19, 1 AM — quietSep 19, 4 AM — quietSep 19, 7 AM — 2 pieces · 1 article · 1 post — Newswires 1, Mastodon 1Sep 19, 10 AM — 1 piece · 1 comment — Reddit 1Sep 19, 1 PM — 1 piece · 1 comment — Reddit 1Sep 19, 4 PM — quietSep 19, 7 PM — quietSep 19, 10 PM — quietSep 20, 1 AM — quietSep 20, 4 AM — quietSep 20, 7 AM — quietSep 20, 10 AM — quietSep 20, 1 PM — quietSep 20, 4 PM — quietSep 20, 7 PM — quietSep 20, 10 PM — quietSep 21, 1 AM — quietSep 21, 4 AM — quietSep 21, 7 AM — quietSep 21, 10 AM — quietSep 21, 1 PM — quietSep 21, 4 PM — quietSep 21, 7 PM — quietSep 21, 10 PM — quietSep 22, 1 AM — quietSep 22, 4 AM — quietSep 22, 7 AM — quietSep 22, 10 AM — quietSep 22, 1 PM — quietSep 22, 4 PM — quietSep 22, 7 PM — quietSep 22, 10 PM — quietYesterday, 1 AM — quietYesterday, 4 AM — quietYesterday, 7 AM — quietYesterday, 10 AM — quietYesterday, 1 PM — quietYesterday, 4 PM — quietYesterday, 7 PM — quietYesterday, 10 PM — quietToday, 1 AM — quiet 1–23–6
Sep 13Sep 14Sep 15Sep 16Sep 17Sep 18Sep 19Sep 20Sep 21Sep 22now · 3:52 AM ET
  1. 6

    SportsLine expert Eric Cohen releases exact score predictions for Week 2

    CBS Sports publishes Eric Cohen's specific score predictions for every Week 2 NFL game based on the model's analysis.

    1. first by The Globe and Mail, 6d ago · also ESPN NFL, ESPN, The New York Times, Sky Sports, Chicago Tribune, Boston Globe +9

      16 more headlines
    2. first by CBS Sports, 7d ago · also Yahoo, Sports Illustrated, Blitz Sports Media, Democrat and Chronicle, The Detroit News, ESPN NFL +8

      46 more headlines
    9 more claims →
    • Josh Allen goes deep to a WIDE OPEN Josh Palmer for SIX DETvsBUF on Prime Video Stream on @NFLPlus

      @NFLX6d ago824▲view on X ↗
    2 more of the top 3 · 74 posts in this stretch
    • kfitz134.bsky.social

      The Buffalo Bills win their first game in Highmark Stadium, defeating the Detroit Lions 41-31. The Bills won.

      kfitz134.bsky.socialBluesky6d ago123▲view on Bluesky ↗
    • thejapantimes@mastodon.social

      Josh Allen threw a perfect housewarming for Buffalo's brand new NFL stadium as the Bills comfortably beat the Detroit Lions 41-31 on Thursday. https://www. japantimes.co.jp/sports/2026/0 9/18/more-sports/bills-lions-stadium/?utm_medium=Social&utm_source=mastodon # moresports # buffalobills # detroitlions # nfl # joshallen

      thejapantimes@mastodon.socialMastodon5d ago1▲view on Mastodon ↗
    all of them →
  2. 5

    CBS Sports compiles Week 2 odds, start times, and betting lines with picks

    CBS Sports aggregates the Week 2 NFL odds, spreads, start times, and SportsLine model picks for all games.

    1. first by SportsLine, 8d ago · also USA Today, CBS Sports

      3 more headlines
  3. 4

    CBS Sports publishes full Week 2 score predictions from model simulations

    CBS Sports releases SportsLine's Week 2 NFL score predictions derived from 10,000 game simulations for every matchup on the schedule.

    1. first by Awful Announcing, 7d ago · also Sporting News, Yahoo Sports

      1 more headline
    2. 1 outlet first by CBS Sports, 8d ago · read ↗

  4. 3

    SportsLine computer model releases Week 2 picks backing Seahawks and Buccaneers

    CBS Sports reports that SportsLine's computer model, which simulates every game 10,000 times and has a 53-39 record on top-rated picks since 2024, has backed the Seahawks at -4.5 to cover against Arizona and the Buccaneers at -8.5 to cover against Cleveland. The model notes Seattle's 8-1 ATS record in nine straight meetings with Arizona and forecasts double-digit wins in both games well over 60% of the time.

    “The Seahawks are forecasted to win by double digits, prevailing versus the spread well over 60% of the time in an A-rated pick.”
    — SportsLine (via CBS Sports)
    1. first by CBS Sports, 8d ago

      1 more headline
  5. 2

    Yahoo Sports previews Week 2 matchups with game-by-game predictions

    Yahoo Sports' predictions focus on several key Week 2 contests: Buffalo is picked to edge Detroit in Thursday Night Football despite both teams' defensive weaknesses; Chicago's high-powered offense (59 points, 552 yards in Week 1) faces Minnesota's aggressive defense; and Philadelphia is expected to dominate Tennessee. The analysis notes uncertainty at Falcons QB with both Tua Tagovailoa (oblique) and Michael Penix Jr. (knee) in question.

    “Josh Allen wins a shootout against Jared Goff, with Buffalo coming out with a two-to-zero record but renewed concerns about its run defense.”
    — Yahoo Sports
    1. first by Yahoo Sports, 9d ago

    • pro-football-reference.com

      Josh Allen has entered the NFL's top 20 leaderboard for rushing touchdowns, tying Frank Gore and Ottis Anderson. 📈 See the full leaderboard:

      pro-football-reference.comBluesky9d ago11▲view on Bluesky ↗
  6. 1

    Yahoo Sports publishes Week 2 odds for all games

    Yahoo Sports releases the full betting odds and spreads for every Week 2 NFL matchup, noting Week 1 delivered surprises including the Cardinals defeating the Chargers 26-14 and the Saints nearly overcoming a 21-0 deficit to Detroit.

    1. first by Yahoo Sports, 9d ago

Also covered reported alongside — the timeline has no entry for these yet

  1. first by Sports Illustrated, 6d ago · also Yahoo Sports, Pride Of Detroit, Sporting News

    2 more headlines
  2. first by nbcsports.com, 6d ago · also NY Post, New York Post, Yahoo Sports

    1 more headline
  3. first by ESPN NFL, 6d ago · also ESPN, Yahoo Sports

    4 more headlines
  4. first by Yahoo Sports, 7d ago · also Miami Herald, Detroit Free Press

    3 more headlines
  5. first by Sportsnet.ca, 6d ago · also TSN, NY Post

    2 more headlines
  6. first by Yahoo Sports, 7d ago · also WKBW, Toronto Star

    2 more headlines
  7. first by Yahoo Sports, 6d ago · also Sporting News, Buffalo Rumblings

    2 more headlines
  8. first by Yahoo Sports, 6d ago · also Pride Of Detroit, Buffalo Rumblings

    1 more headline
  9. first by Yahoo Sports, 6d ago · also Sporting News

    4 more headlines
  10. first by Yahoo Sports, 6d ago · also Democrat and Chronicle

    2 more headlines

and 39 smaller pieces

What people are saying 20 voices from 4 sites · best of 78 · verbatim