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1. 4 Sep 22

   Lead researcher emphasizes need for larger trials despite encouraging pilot results

   Russell Wells told Newsweek that the findings are encouraging but larger clinical trials are needed to confirm whether time-restricted eating can actually slow disease progression, framing the approach as one that may help protect brain cells rather than as a proven treatment.

   “One of the most encouraging findings was that time-restricted eating appeared to reduce a key marker of neurodegeneration while remaining safe and sustainable for participants. The results suggest this simple dietary approach may help protect brain cells, but larger clinical trials are needed.”

   1. 1 outlet Simple Change in When You Eat May Slow One Degenerative Condition

      first by Newsweek, 1d ago

2. 2 days quiet
3. 3 Sep 19

   Study design addressed safety concerns about weight loss in Huntington's patients

   Researchers had initially been uncertain whether intermittent fasting would be safe because unintended weight loss is already a concern for many Huntington's patients. The 20-study participants were encouraged to maintain normal calorie intake, and researchers closely monitored weight throughout; participants maintained both body weight and lean muscle mass.

   “Weight loss is a major challenge for many people with Huntington's disease, so asking them to eat within a limited time window seemed counterintuitive. What was exciting about this study is that participants were able to maintain their weight while showing signs that the intervention may be positively affecting the disease itself.”

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     Interesting! 8h intermittent fasting doesn't not work for Huntington's. More studies needed: sign me up! https:// news.ohsu.edu/2026/09/17/inter mittent-fasting-shows-promise-in-slowing-huntingtons-disease-progression # huntingtonsdisease # science

     andygates@mastodon.socialMastodon4d ago1▲view on Mastodon ↗
4. 1 day quiet
5. 1 Sep 17

   Study shows time-restricted eating reduces neurodegeneration biomarker by 13 percent

   Blood levels of neurofilament light, a marker of nerve cell damage that typically rises in Huntington's disease, fell by an average of 13 percent in study participants. On the Unified Huntington's Disease Rating Scale, participants improved by an average of 0.5 points, compared to the typical annual decline of one point.

6. 2 Sep 17

   OHSU study finds time-restricted eating safe and potentially beneficial in Huntington's disease

   Oregon Health & Science University researchers published findings from a 12-week pilot study in Nature Metabolism showing that people with early-stage Huntington's disease could safely follow intermittent fasting while limiting food to a 6-8 hour window daily. Participants maintained their weight and showed improvements in disease severity measures and cellular energy production.

   “This is the first time this approach has been formally studied in people with Huntington's disease. We found that participants were able to follow the eating schedule, maintain their weight and show encouraging improvements in clinical and biological measures.”

   1. 1 outlet Intermittent fasting could slow down Huntington’s disease

      first by The Telegraph, 4d ago

   2. 1 outlet Intermittent fasting shows promise in slowing Huntington's disease progression

      first by Medical Xpress, 6d ago

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