Study links chronic stress to hidden heart inflammation, 43% higher stroke risk
Imperial College London analysis of 480,000 UK adults finds stress-driven inflammation silently damages the heart years before symptoms appear.
What to know
- A study of 480,000 UK adults found that chronic stress-driven inflammation increases heart attack and stroke risk by 43 percent in the most-inflamed group, with structural heart damage developing silently years before symptoms.
- Socioeconomic disadvantage, psychological stress, smoking, and obesity are key drivers of the inflammatory damage; no effective drugs currently treat this type of inflammation.
- Lifestyle interventions—maintaining healthy weight, Mediterranean diet—and addressing mental health conditions may reduce inflammation, and researchers suggest social disadvantage is an important public health intervention target.
The study findings are personally relevant and merit deeper investigation into stress and heart health.
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“Any sources for research I can look further into this? Experiencing a toxic business partnership that has killed my motivation and creativity.”
PM_COFFEE_TO_ME · reddit ↗
“Chronic inflammation is complicated, but we know it's tied to our health and driven by a range of lifestyle and economic factors – meaning people may be at more risk just because of their surroundings, their economic status, their family's health and their lifestyle.”
Professor Declan O'Regan, Lead researcher, Imperial College London · Newsweek ↗
Professor Declan O'Regan Lead researcher, Imperial College LondonImperial College London and MRC Laboratory of Medical Sciences Research institutions
How it unfolded 3 developments, newest first · click a bar or a number to jump articlespostscomments
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Researchers highlight lack of effective drugs but identify lifestyle interventions and mental health link
O'Regan noted that no effective drugs currently treat this type of chronic inflammation, though new therapies are in trial. He highlighted that maintaining healthy weight and following a Mediterranean diet can reduce inflammation modestly, and suggested that chronic hidden inflammation may be a key mechanism linking mental health conditions to increased heart disease risk.
“We know that people with mental health conditions are at increased risk of heart disease - this study suggests that chronic hidden inflammation may be a key factor linking the two conditions.”
— Professor Declan O'Regan -
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https:// lms.mrc.ac.uk/chronic-stress-m ay-trigger-hidden-inflammation-that-damages-the-heart/
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Researchers identify socioeconomic factors and lifestyle as key drivers of inflammatory heart damage
The study found that higher inflammation levels are associated with socioeconomic disadvantage, psychological distress, smoking, and excess body fat. Professor O'Regan emphasized that social disadvantage is emerging as a key public health risk factor for heart disease, and that chronic stress from multiple causes can trigger long-term inflammation without initial symptoms.
“Chronic stress, from many different causes, may trigger long-term inflammation with no initial symptoms. But we can now see how this leads to adverse changes in the heart that precede any symptoms of cardiovascular disease.”
— Professor Declan O'Regan - 1 day quiet
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Imperial College study reveals chronic stress drives silent heart inflammation in 480,000-person analysis
Researchers analyzed blood work and heart imaging data from 480,000 UK adults and found that people with the highest inflammation levels had a 43 percent higher risk of heart attack and stroke compared to those with the lowest levels. The study, published in the European Journal of Preventive Cardiology, shows these structural heart changes develop silently, years before any symptoms appear.
“Millions of people could be living with hidden inflammation, which is slowly changing their heart and causing long term damage - increasing the risk of heart attack and stroke.”
— Professor Declan O'Regan -
first by medicalxpress.com, 6d ago · also The Hippocratic Post, News-Medical, India News Network, Medical Dialogues, Cardiovascular Business
6 more headlines
- Chronic stress may trigger heart damage The Hippocratic Post · 5d ago
- Chronic stress and inflammation cause silent structural heart damage News-Medical · 5d ago
- Chronic Stress Linked to Hidden Heart Inflammation Risk India News Network · 5d ago
- Chronic stress linked to higher heart attack risk: Study | The study was done by Imperial College London | Inshorts inshorts.com · 5d ago
- Chronic Stress Could Drive Hidden Inflammation Linked to Heart Damage: Study Medical Dialogues · 5d ago
- Chronic stress linked to heart damage, other risks in new imaging study Cardiovascular Business · 5d ago
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first by Science Daily, 2d ago
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