Meta-analysis of 51 studies links ultra-processed foods to major disease risks
Research pooling data from 8.8 million participants finds each 100g daily increase associates with higher cardiovascular, cancer, and mortality risks.
What to know
- A meta-analysis of 51 studies covering 8.8 million participants found each extra 100g of ultra-processed foods daily links to a 14% higher cardiovascular risk, 4% higher cancer risk, and 3% higher all-cause mortality.
- Ultra-processed food consumption showed dose-response associations with multiple chronic conditions: 24% higher metabolic syndrome/diabetes, 27% higher depression/anxiety, and 31% higher digestive disease risk.
- Researchers identified potential mechanisms including gut microbiome damage, inflammation, insulin resistance, and a 'cocktail effect' from combined food additives.
- Approximately 60% of the American diet consists of ultra-processed foods, often chosen because they are cheaper than healthier alternatives.
“The findings suggest ultra-processed-food factors beyond nutrients – such as changes to foods' cellular structure, loss of beneficial chemical compounds, additives and chemicals from packaging – may create health risks not addressed by traditional nutrition metrics or policies”
Dariush Mozaffarian · The Independent ↗
Dr. Xiao Liu Lead study author, physicianDuke-NUS Medical School researchers Study researchersDariush Mozaffarian Cardiologist, Tufts University
How it unfolded 2 developments, newest first · click a bar or a number to jump articlesposts
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Lead researcher Dr. Xiao Liu calls for dietary shift away from ultra-processed foods
Dr. Xiao Liu, lead author and physician at Sun Yat-Sen Memorial Hospital, emphasized to ABC News that modern diets and food may not be safe and called for increased vegetable consumption and reduced ultra-processed food intake.
“In our modern society, our diet and food is maybe not safe … we should eat more vegetables and reduce the ultra-processed food to make us healthier…”
— Dr. Xiao Liu -
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https://www. europesays.com/us/1081467/ Ultra-processed foods raise chronic disease risk, large study finds # Food # Food &Drink # Health # Lifestyle # Nutrition # SnackFoods # UnitedStates # UnitedStates # US # Wellness
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Study identifies potential mechanisms: gut microbiome damage, inflammation, and food additives — Researchers noted that lab studies suggest ultra-processed foods' altered physical composition may adversely affect the gut microbiome and promote inflammation and insulin resistance. Compounds formed during processing, such as acrylamide and acrolein, have been associated with higher cardiovascular disease incidence. Emerging evidence suggests multiple additives may exert a 'cocktail effect' on human health.
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Study findings show dose-response relationship between ultra-processed food and cardiovascular risk — The analysis found that each additional 100 grams of ultra-processed foods daily was associated with an 11% higher hypertension risk, 14% higher cardiovascular event risk, 4% higher cancer risk, and 3% higher all-cause mortality. Every 10% increase in weight per energy intake from ultra-processed foods was linked to a 16% higher metabolic syndrome/diabetes risk.
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Researchers recommend reducing ultra-processed food consumption for chronic disease prevention
Study authors concluded that given the clustering of ultra-processed food-related chronic diseases as multimorbidity, reducing consumption and replacing with minimally processed alternatives may be relevant for chronic disease prevention and primary care management.
“Given that UPF related chronic diseases often cluster as multimorbidity, reducing consumption of UPFs (ultra processed foods) and replacing them with minimally processed alternatives may be relevant for chronic disease prevention and primary care management…”
— Study authors -
background
Meta-analysis of 51 studies published on ultra-processed food health risks — Researchers including those from Duke-NUS Medical School published a pooled data analysis in Family Medicine and Community Health examining 51 prospective cohort studies from the Americas, Europe, Asia, and Oceania involving 8,819,894 participants aged 23-77, with follow-up periods ranging from 2 to 32 years.
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2 outlets Extra 100gm Of Ultra-Processed Foods Daily Linked To 14 Per Cent Higher Risk Of Heart Event: Study
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